Using sound vibrations and pulses of near-infrared light, a scientist has developed a new 'virtual biopsy' device that can quickly determine a skin lesion's depth and potential malignancy without using a scalpel.

2019-06-13

Using sound vibrations and pulses of near-infrared light, a scientist has developed a new 'virtual biopsy' device that can quickly determine a skin lesion's depth and potential malignancy without using a scalpel.

A homing beacon for chemotherapy drugs

2019-06-12

Killing tumor cells while sparing their normal counterparts is a central challenge of cancer chemotherapy. If scientists could put a 'homing beacon' in tumors, they could attract these medicines and reduce side effects caused by the drugs acting on healthy cells. Now, researchers have made a hydrogel that, when injected near tumors in mice, recruits drugs to shrink the tumor with fewer side effects. They report their results in ACS Central Science.

Unhealthy gut promotes spread of breast cancer

2019-06-10

An unhealthy, inflamed gut causes breast cancer to become much more invasive and spread more quickly to other parts of the body, new research suggests.

A molecular glue to overcome cancer drug resistance?

2019-06-07

Researchers have discovered a small molecule drug that can stop cancer cells from becoming resistant to chemotherapy. The new compound, which was tested in an animal model of melanoma, could serve as a powerful adjuvant to make current chemotherapies more effective. It works by thwarting cancer's ability to survive, evolve, and adapt to the onslaught of DNA damage wrought by traditional chemotherapy drugs like cisplatin.

A Gut Feeling: Microbiome Changes May Mean Early Detection of Colorectal Cancer

2019-06-12

Most sporadic colorectal cancers can develop over decades. Recent studies showed that the gut microbiome has possible diagnostic potential for health and disease. Researchers assessed fecal samples from patients who underwent colonoscopy to study the relationship between gut microbiota and colorectal cancer. They found specific markers that could discriminate cases of colorectal cancer from healthy samples. This posits that colorectal cancer is not only a genetic, but also a microbial disease

DNA Nanorobots Target HER2-Positive Breast Cancer Cells

2019-06-05

About 20% of breast cancers make abnormally high levels of a protein called human epidermal growth factor receptor 2 (HER2). When displayed on the surface of cancer cells, this signaling protein helps them proliferate uncontrollably and is linked with a poor prognosis. Now, researchers have developed a DNA nanorobot that recognizes HER2 on breast cancer cells, targeting them for destruction

Drug makes tumors more susceptible to chemo

2019-06-06

Researchers have discovered a potential drug compound that can block a mutagenic DNA repair pathway that helps cancer cells survive chemotherapy. When they treated mice with this compound along with cisplatin, a DNA-damaging drug, tumors shrank much more than those treated with cisplatin alone.

Identifying colorectal cancer subtypes could lead to improved treatment decisions

2019-06-12

Identifying a metastatic colorectal cancer patient's Consensus Molecular Subtype could help oncologists determine the most effective course of treatment. For example, Survival for CMS1 patients on bevacizumab was twice that of those on cetuximab, whereas survival for CMS2 patients on cetuximab was six months longer than for bevacizumab.

Cancer survivors predicted to number over 22 million by 2030

2019-06-11

There were more than 16.9 million Americans with a history of cancer on Jan. 1, 2019, a number that is projected to reach more than 22.1 million by 2030 based on the growth and aging of the population alone.

A 'one-two punch' to wipe out cancerous ovarian cells

2019-06-11

Researchers have developed a two-step combination therapy to destroy cancer cells. They show the superior therapeutic effectiveness of the 'one-two punch' on cells of ovarian cancer patients, based on manipulation of the state of cellular aging.

Molecular chatter makes for a 'hot tumor'

2019-06-10

A new study has deciphered a complex molecular conversation between cancer and immune cells that is key to orchestrating the successful invasion of tumors by T cells that kill cancer cells.

New radiotracer can identify nearly 30 types of cancer

2019-06-07

A novel class of radiopharmaceuticals has proven effective in non-invasively identifying nearly 30 types of malignant tumors. Using 68Ga-FAPI PET/CT, researchers were able to image the tumors with very high uptake and image contrast, paving the way for new applications in tumor characterization, staging and therapy.

Physics could answer questions about breast cancer spreading to bones

2019-06-06

To fully understand why breast cancer spreads, or metastasizes, you must also consider the how. That's what researchers in a biophysics and imaging laboratory in the School of Science at IUPUI did as they studied the mechanics of cell migration, which can possibly explain how cancer cells generate enough force to move from the primary tumor site through the body and then settle into bones.

Nanoparticles stimulated by microwaves to combat cancer

2019-06-04

A physicist has proposed a new concept for treating cancer cells.

Vitamin D could help cancer patients live longer

2019-06-04

Physicians have found that vitamin D, if taken for at least three years, could help cancer patients live longer. The findings suggest that the vitamin carries significant benefits other than just contributing to healthy bones.

Immunotherapy drug found safe in treating cancer patients with HIV, study suggests

2019-06-03

The results of a new study suggest that patients living with HIV and one of a variety of potentially deadly cancers could be safely treated with the immunotherapy drug pembrolizumab, also known by its brand name, KEYTRUDA.

How cells in the body can sense cancer

2019-06-05

Fresh insights into how cells alert the body when they are in danger of becoming cancerous could open new doors in the search for therapies. Scientists have discovered that regular cells can take on characteristics of immune cells, which can send warning signs when they are stressed or in danger.

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Using sound vibrations and pulses of near-infrared light, a scientist has developed a new 'virtual biopsy' device that can quickly determine a skin lesion's depth and potential malignancy without using a scalpel.

A homing beacon for chemotherapy drugs

Unhealthy gut promotes spread of breast cancer

A molecular glue to overcome cancer drug resistance?

A Gut Feeling: Microbiome Changes May Mean Early Detection of Colorectal Cancer

DNA Nanorobots Target HER2-Positive Breast Cancer Cells

Drug makes tumors more susceptible to chemo

Identifying colorectal cancer subtypes could lead to improved treatment decisions

Cancer survivors predicted to number over 22 million by 2030

A 'one-two punch' to wipe out cancerous ovarian cells

Molecular chatter makes for a 'hot tumor'

New radiotracer can identify nearly 30 types of cancer

Physics could answer questions about breast cancer spreading to bones

Nanoparticles stimulated by microwaves to combat cancer

Vitamin D could help cancer patients live longer

Immunotherapy drug found safe in treating cancer patients with HIV, study suggests

How cells in the body can sense cancer

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Using sound vibrations and pulses of near-infrared light, a scientist has developed a new 'virtual biopsy' device that can quickly determine a skin lesion's depth and potential malignancy without using a scalpel.

A homing beacon for chemotherapy drugs

Unhealthy gut promotes spread of breast cancer

A molecular glue to overcome cancer drug resistance?

A Gut Feeling: Microbiome Changes May Mean Early Detection of Colorectal Cancer

DNA Nanorobots Target HER2-Positive Breast Cancer Cells

Drug makes tumors more susceptible to chemo

Identifying colorectal cancer subtypes could lead to improved treatment decisions

Cancer survivors predicted to number over 22 million by 2030

A 'one-two punch' to wipe out cancerous ovarian cells

Molecular chatter makes for a 'hot tumor'

New radiotracer can identify nearly 30 types of cancer

Physics could answer questions about breast cancer spreading to bones

Nanoparticles stimulated by microwaves to combat cancer

Vitamin D could help cancer patients live longer

Immunotherapy drug found safe in treating cancer patients with HIV, study suggests

How cells in the body can sense cancer