Title: REFERENCE VALUES OF MYOCARDIAL T1, T2 AND T2* RELAXATION TIMES, 1.5 T, IN HEALTHY LATIN AMERICAN PATIENTS

Abstract:

The Cardiac magnetic resonance (CMR) is an invaluable tool for diagnosis and risk stratification in a wide spectrum of heart diseases. To determine the reference values of myocardial T1 relaxation times, T2 and T2*, in our population to justify their clinical interpretation in the tissue evaluation of different cardiovascular diseases. We included, 27 healthy volunteers (13 men and 14 women) between 25 and 69 years of age. A short CMR protocol was performed in a 1.5 T resonator, using the MOLLI technique, in T1 mapping. The global and segmental T1 values were quantified, using the American Heart Association (AHA) model, for the entire left ventricle, in three short-axis slices (basal, middle, and apical). The post process and analysis of the data with the commercialized software, Cvi42. The mean global myocardial T1 value was 1069.41 ms with a SD of 38.73 ms. Among the age groups, the group <34 years had the lowest global T1 values (1057 SD 33 msec), and the group of 35 -44 years obtained the highest values (1100 SD 50 msec), so no relationship was found between the linear increase in age and the variability of relaxation times. Between both sexes, men had lower global T1 values than women (1049 vs 1086). Regarding the value of T2, our average was 51.58 msec. Finally, T2*: 36.61 msec. The native T1 ranges can serve as a basis for the quantitative characterization of the myocardium in the context of focal or diffuse diseases, in patients with infarcts, storage and inflammatory diseases. Therefore, we consider that we have presented the only database of myocardial T1 relaxation times carried out in a healthy Latin American population, and it is a fundamental need for its subsequent comparison with studies in populations with similar characteristics.

Biography:

González Nelsy Coromoto has completed his PhD at the age of 24 years from Los Andes University and postdoctoral studies from Universidad Nacional Experimental de México. She is the director of cardiovascular imaging of CT Scanner México. She has published more than 30 papers in reputed journals and has been serving as an editorial board member of repute.