Title: International Healthcare and Marketing
Abstract:
Sildenafil (100 mg) vasodilated epicardial coronary arteries (+6.9 ± 1.3%, p < 0.0001). Coronary epicardial and microvascular responses with acetylcholine and cold-pressor testing improved, with a greater enhancement in patients with CAD and endothelial dysfunction. Verapamil responses were unchanged. Both resting and adenosine diphosphate-stimulated platelet IIb/IIIa receptor activation was inhibited by sildenafil (p < 0.05). Brachial arteries dilated in response to sildenafil in controls. Peak flow-mediated dilation was similar, but the duration of hyperemia was prolonged after sildenafil administration (p < 0.001). Compared with placebo, ISDN improved myocardial ischemia during exercise (p < 0.05), whereas the effect of sildenafil was intermediate between the two.
Biography:
Samer Ellahham has served as Chief Quality Officer for Sheikh Khalifa Medical City since 2009. He has led the development of the quality and safety program that has been highly successful and visible and has been recognized internationally .