Longdom Conferences

Speaker

Mar 19-20, 2020    London, UK

World Summit on Infectious Diseases and Therapeutics

Atsbeha Gebreegziabxier Weldemariam
02:45 PM-03:15 PM

Atsbeha Gebreegziabxier Weldemariam

Universitat Rovira I Virgili, Spain Ethiopia

Title: Nationwide Seroprevalence of Hepatitis B Virus Infection in Ethiopia: A Population- Based cross-sectional Study

Abstract:

Background: Hepatitis B virus (HBV) infection is a major cause of morbidity and mortality globally. In Ethiopia, there is a paucity of nationwide HBV sero-prevalence. The aim of this study is to assess sero-prevalence of HBV infection and identify associated risk factors in the country.

Methods: A population-based cross-sectional study was conducted from stored serum samples of the nationwide Non-communicable Diseases (NCDs) step-wise survey among people aged 15-69 years in all geographical areas in the country. A mix of sampling approach (stratified, three-stage cluster sampling, simple random sampling and Kish method) was used to select the study settings and the study participants.

Findings: There were a total of 7789 study participants: 26.4% were from urban areas and 59.5 % were females. The nationwide sero-prevalence of HBsAg was 9.4% (95% CI, 8.3-10.7) with significant regional variation having its highest burden in Afar Regional State (28.8% (95% CI 21.2-37.8) and lowest in Harari Regional State 4.9% (95% CI, 2.0-11.8).

This national study revealed significantly, higher prevalence of anti-HBsAg in males compared to females [10.3% vs 8.4%; p=0.004].

Conclusion: The findings of this study showed high endemicity level of HBV infection in Ethiopia, calling for strengthened HBV infection prevention, care and treatment services.

Keywords: Hepatitis B Virus, HBsAg, HBV Seroprevalence, Population Based Study, Ethiopia.

Biography:

Atsbeha Gebreegziabxier Weldemariam is a Nanoscience by profession and He complete his MSc in Nanoscience and Nanotechnology, Universitat Rovira I Virgili, Spain. Currently He works in Ethiopian Public Health Institute, Ethiopia for Ten years which involved as a researcher in clinical and biomedical research and Nanomedicine research (focused on infectious diseases including HIV, TB, and HBV/HCV) and as a public health professional coordinating and participating in national HIV and HIV/TB survey and surveillance, and in evaluating national programs related to HIV, HIV/TB and HCV/HBV. He has published scientific articles in peer-reviewed journals and more than 16 training awards in USA, Europe, Japan, Africa etc. Travel experience in Europe, USA, Japan, and Africa.

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A single dose of an antibody-based treatment can prevent HIV transmission from mother to baby, new nonhuman primate research suggests for the first time. This is the first time a single dose of broadly neutralizing antibodies given after viral exposure has been found to prevent infection in nonhuman primate newborns.

A molecular switch for stomach disease

2020-01-08

A research team has revealed a new mechanism which controls the causes of infection with H. pylori, triggering the development of stomach diseases. It is hoped that these findings will lead in time to new therapies.

First robust cell culture model for the hepatitis E virus

2020-01-13

A mutation switches the turbo on during virus replication.

New strategy in the fight against antibiotic resistance

2020-01-14

Bioscience engineers have developed a new antibacterial strategy that weakens bacteria by preventing them from cooperating. Unlike with antibiotics, there is no resistance to this strategy.

New species of antibiotic-resistant bacteria found in infected wound

2020-01-21

A hitherto unknown antibiotic-resistant bacteria species, in the same family as E. coli and Salmonella spp., has been found and classified in Sweden. The proposed taxonomic name of the species -- the first of the new genus -- is Scandinavium goeteborgense, after the city of Gothenburg, Sweden, where the bacterium was isolated and the research was done.

Researchers reverse HIV latency, important scientific step toward cure

2020-01-22

Overcoming HIV latency -- induction of HIV in CD4+ T cells that lay dormant throughout the body - is a major step toward creating a cure for HIV. For the first time, scientists have shown that a new approach can expose latent HIV to attack in two different animal model systems with little or no toxicity.

Exposure to diesel exhaust particles linked to pneumococcal disease susceptibility

2020-01-23

A new study shows that exposure to diesel exhaust particles (DEPs) can increase an individual's susceptibility to pneumococcal disease.

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