Title: Integration of gold nanoparticles in PDMS microfluidics for lab-on-a-chip plasmonic biosensing of growth hormones

Abstract:

Gold nanoparticles were synthesized in a poly (dimethylsiloxane)(PDMS) microfluidic chip by using an in-situ method, on the basis of reductive properties of the cross-linking agent of PDMS. The proposed integrated device was further used as a sensitive and low-cost LSPR-based biosensor for the detection of polypeptides. Synthesis of nanoparticles in the microfluidic environment resulted in improvement of size distribution with only 8% variation, compared with the macro-environment that yields about 67% variation in size. The chemical kinetics of the in-situ reaction in the microfluidic environment was studied in detail and compared with the reaction carried out at the macro-scale. The effect of temperature and gold precursor concentration on the kinetics of the reaction was investigated and the apparent activation energy was estimated to be E a⁎= 30 kJ/mol. 

Biography:

Hamid Sadabadi is an entrepreneur and researcher in the field of Microfluidics, Lab-on-a-chip and sensors/biosensors. He has completed his PhD in microfluidic from Concordia University in Montreal. ... He is the currently CTO of Wireless Fluidics, a sensing technology development start-up.