Niсkolai A. Tchurikov
Niсkolai A. Tchurikov, Doctor of Sciences (D. Sci.- molecular biology), now is a Head of the Department of Epigenetic Mechanisms of Gene Expression Regulation, Engelhardt Institute of Molecular Biology, Moscow, Russia. He got his Medicine Doctor's degree (M.D.) at Stavropol State Medical Institute in 1972. In 1977 he got his Molecular Biology Ph.D. at Engelhardt Institute of Molecular Biology, Moscow, USSR. Winner of the State Award of the USSR for the discovery on the molecular level of mobile elements in eukaryotes, 1983. 1977 – Ph.D.- “Discovery and properties of mobile element Dm225 in Drosophila genome”. 1989 – D.Sci. – “Molecular organization of the cut locus in Drosophila melanogaster”. In 1977-1980 discovered at the molecular level mobile genetic elements in Drosophila and clusters of different mobile elements. In 1981-1989 cloned the entire complex cut locus from Drosophila and detected multiple transposition events in the locus and several new mobile elements. In 1988-2000 detected the physical capacity of DNA and RNA molecules to form parallel duplexes. In 1998 sequenced completely a novel LTR element, burdock. In 1988-2015 detected large chromosomal domains corresponding to the units of coordinated gene expression, trans-RNAi. Current interests – epigenetic mechanisms in the regulation of gene expression, regulation of siRNA and piRNA pathways of silencing, the study of higher-order chromosomal structures by 4C, and development of RNAi approach for AIDS/HIV treatment.