Fungal pathogenesis is the process by which fungi infect and cause disease in a host. Not all fungi are pathogens and have the ability for pathogenesis, also known as virulence. Pathogenic organism look like typical molds which can cause dangerous infections. Numerous sorts of microbes are available like candida, aspergillus, cryptococcus, and so on. Pathogenic fungi have an enormous impact on human health. Most people are aware of some of the superficial infections caused by fungi. 

The immune defence mechanisms against fungal infections are of two types – innate immunity and adaptive immunity. Cell mediated immunity plays a major role against fungal infections by destroying fungus and protects body from reinfection.

The importance of fungal infections has increased over the last decades. Emerging fungal infections is also cause of significant morbidity and mortality. New dimorphic fungal pathogens have emerged including emergomyces which cause disseminated mycoses globally, primarily in HIV infected patients and blastomyces helicus and B. percursus are causes of a typical blastomycosis.

Aspergillosis is an infection caused by a type of mold (fungus). The illnesses resulting from aspergillosis infection usually affect the respiratory system, but their signs and severity vary greatly. The mold that triggers the illnesses, aspergillus, is everywhere — indoors and outdoors. Signs and symptoms depend on which organs are affected generally are fever and chills.

Candidiasis a fungal infection typically on the skin or mucous membranes caused by candida. When it affects the mouth, it is commonly called thrush. Signs and symptoms include white patches on the tongue or other areas of the mouth and throat. Other symptoms may include soreness and problems swallowing.

The most widespread therapies for fungal infections are antifungal drugs, such as small molecules, monoclonal antibodies and radioimmunotherapy (RIT) and antifungal treatments include the medicines clotrimazole, miconazole or econazole.