Title: Use of Cell Therapy in solid organ transplantation:

Abstract:

The use of adjusted immunosuppressants has significantly improved graft and patient survival in the early phase after transplantation, but long-term results are often inadequate due to the development of chronic transplant rejection. In addition, long-term immunosuppression has serious side effects that can seriously affect a patient`s survival and quality of life. Achieving tolerance in the long term without the use of immunosuppressants is the ultimate goal of most of the research in the field of solid organ transplantation. Several strategies, including per graft-versus administration of non-hematopoietic immunomodulatory cells, can safely and effectively induce resistance in preclinical models of solid organ transplantation. In my next series of posts, I will be focusing on various evidence of the use of Mesenchymal stem cells in inducing long-term graft tolerance.

Biography:

Renna Rathod Passionate Cell biology scientist with 13 years of experience in academia and industry in national and international settings. she has expertise in culturing and differentiation of human and mouse pluripotent stem cells into different cell types for disease modeling and regenerative purpose, Immuno-oncology (CAR-T), and Viral vector. With her Ph.D. from the University of Wuerzburg and other international collaborations, she has demonstrated the capacity to lead a team, work in a team environment as well as independently and bring several collaborations.